Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. However, with an organ transplant, this process is harmful to your new organ. CELLCEPT (mycophenolate mofetil) is a prescription medicine to prevent rejection (antirejection medicine) in people who have received a kidney, heart or liver transplant. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. If your doctor has prescribed CellCept and youre interested in using mycophenolate mofetil instead, talk with your doctor. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. However, clinical guidelines recommend using CellCept for lupus in adults who also have signs of kidney disease. They can be prescribed to adults and children.. It is used with other medicines (eg, cyclosporine, steroid medicine) to lower the body's natural immunity in patients who receive organ transplants (eg, kidney, heart, or liver). This can increase the risk of side effects and toxicity. CellCept is available in the following forms and strengths: The first oral dose of CellCept is given as soon as possible after a kidney, heart, or liver transplant. However, this list doesn't include all possible mild side effects. Avoid inhaling the powder from the capsule or allowing the powder or the oral liquid to touch your skin or eyes. It can also interact with certain supplements as well as certain foods. Also tell them about any vitamins, herbs, and supplements you use. Researchers wanted to see how effective each treatment was at preventing treatment failure. The Leukemia & Lymphoma Society is a 501(c)(3) organization, and all monetary donations are tax deductible to the fullest extent allowed by tax laws. This medicine can cause a miscarriage or birth defects, especially during the first 3 months of pregnancy. However, if its within 2 hours of when youre supposed to take your next dose, just skip the missed dose. Mycophenolate mofetil (CellCept) and mycophenolic acid (Myfortic) are not absorbed equally in the body. Thoroughly cook eggs (no runny yolks) and avoid foods containing raw eggs such as raw cookie dough or homemade mayonnaise. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of mycophenolate delayed-release tablets in children receiving kidney transplants. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre using CellCept. Food safety is important during and after cancer treatments. For autologous transplant patients undergoing chemotherapy treatment only: follow this diet during the first three months after chemotherapy or transplant. In addition to the use listed above, CellCept is also used off-label for other purposes at times. (Organ rejection occurs when the immune system attacks a transplanted organ.). They can recommend ways to treat this side effect. This can reduce its effectiveness in preventing organ . Other medications that affect this process can slow the breakdown of CellCept in your body. Talk with your doctor about the risks and benefits of mycophenolate mofetil. Taking too much may increase the chance of side effects, while taking too little may lead to rejection of your transplanted organ. (Organ rejection occurs when the immune system attacks a transplanted organ. The dose of this medicine will be different for different patients. Its important to note that your results while using CellCept may vary from those seen in clinical studies. The actual price youll pay for any of these drugs depends on the form you use, your treatment plan, your insurance plan, your location, and if applicable, the pharmacy you use. Below are examples of these side effects. Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. If you have questions about using CellCept to help prevent organ rejection, talk with your doctor. This diet was supposed to help individuals with neutropenia learn how to decrease exposure to bacteria and other harmful organisms found in some foods. milkshakes or smoothies made with low-fat dairy, tofu, soy milk, or yogurt. CellCept is a brand-name prescription drug. It can also cause swelling of the ankles. In rare cases, taking CellCept can lead to serious infections that cause sepsis (a life threatening response to an infection) or death. If the medicine gets in your eyes, wash them with plain water. In most cases, you should take CellCept on an empty stomach (1 hour before eating or 2 hours after eating). It is best to take this medicine on an empty stomach, either 1 hour before or 2 hours after meals, unless your doctor tells you otherwise. Theyll likely also check your red blood cell counts regularly during your treatment. The IV infusion* is given by your doctor over a period of about 2 hours, twice per day. Treating scleroderma isnt an FDA-approved use for CellCept. (Cholestyramine is a drug used to treat high cholesterol.). Its also supported by additional data from use in children. As a way of protecting your body, your immune system will try to get rid of it. abnormal blood tests, high blood sugar, high or low blood pressure, fast heart rate. This is especially true for birth control pills that contain the active drug levonorgestrel. The generic is considered to be as safe and effective as the original drug. This article doesnt contain all drugs that may interact with CellCept. Then take your next dose at its usual time. The actual price youll pay depends on your insurance plan, your treatment plan, your location, and if applicable, the pharmacy you use. There arent any herbs or supplements that have been specifically reported to interact with CellCept. To learn about using Prograf in children, talk with your childs doctor. A boxed warning is the most serious warning from the FDA. This helps the body accept the donor organ. Using CellCept in children ages 3 months and older for this purpose is supported by information from clinical studies of adults who have had a liver transplant. Mycophenolate mofetil can make you sunburn more easily. Neutropenia is a condition where you have lower-than-normal levels of neutrophils (a type of white cell). CellCept can cause symptoms that may interfere with your ability to drive, such as: Talk with your doctor if you have questions about driving while using CellCept. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. CellCept is an immunosuppressant (a drug that weakens your immune system). Can diet and exercise reverse prediabetes? Stem cell therapy may help reduce inflammation and build up healthy cells in the body. The dosage for CellCept varies depending on its use. Shake the oral suspension (liquid) before you measure a dose. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. CellCept is rapidly absorbed and converted to its active metabolite, mycophenolic acid. Organ rejection can happen within days or weeks of the transplant. In addition, the amount of weight that people may have lost while using CellCept in these studies isnt known. These drugs make your body less likely to reject a transplanted organ. A boxed warning is the most serious warning from the FDA. Avoid driving or using machines if confusion, dizziness, fainting, lightheadedness, sleepiness, or trembling or shaking of the hands or feet occur during treatment. A boxed warning is the most serious warning from the FDA. Mycophenolate capsules, delayed-release tablets, and tablets should be swallowed whole. To learn more, see the CellCept precautions section below. The information within all other sections is proprietary to Everyday Health. Learn more here. . This medicine should come with a Medication Guide and patient instructions. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. May make these conditions worse. People taking CellCept should avoid eating at least 1 hour before and 2 hours after taking a dose. Below are the typical doses for preventing organ rejection after a heart, kidney, or liver transplant in adults. Do not mix with any other medicine. You and your doctor may decide that other medicines to prevent rejection may be right for you. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). If you have diabetes, you know how important it is to limit sugary foods and beverages. Note: Sex and gender exist on spectrums. Mycophenolate belongs to a group of medicines known as immunosuppressive agents. You do not need to use additional birth control if you use an intrauterine device (IUD), if you have had a tubal ligation, or if your sexual partner has had a vasectomy. Read and carefully follow any Instructions for Use provided with your medicine. Drink high calorie liquids such as juices, soups or shakes if eating solid food is a problem. If you have a lighter skin tone or a family history of skin cancer, your risk of getting skin cancer while using CellCept may be even higher. Other drugs are available that can prevent organ rejection. diarrhoea (dy-a-ree-ah) vomiting. CellCept is FDA-approved to help prevent organ rejection after a heart, kidney, or liver transplant in combination with other immunosuppressants. This diet does not seem to benefit patients in any way. It works by lowering the body's immune system response. Keep the bottle tightly closed when not in use. For allogenic transplant patients: follow the diet until you are off all immunosuppressive therapy such as cyclosporine, prednisone, FK-506 (Tacrolimus) or MMF (CellCept). bloating or swelling of the face, arms, hands, lower legs, or feet, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, pounding, or irregular heartbeat or pulse, muscle cramps in the hands, arms, feet, legs, or face, muscle pain, stiffness, cramps, or weakness, numbness or tingling in the hands, feet, or lips, sores, ulcers, or white spots on the lips or in the mouth, pains in the stomach, side, or abdomen, possibly radiating to the back, sudden high fever or low-grade fever for months. Using this medicine while you are pregnant can harm your unborn baby or cause a miscarriage during the first 3 months. A placebo is a treatment with no active drug.). CellCept and Myfortic have some similar side effects and others that vary. Furthermore, bananas are known to promote healthy blood flow in the body . They may be temporarily stored at temperatures of 59F to 86F (15C to 30C), such as when traveling. Isavuconazole, an antifungal medication, is an example of a drug that can affect how CellCept is broken down in the body. Minimally clinically significant. Possible side effects include: 3Heart- CellCept increases the risk of high blood pressure and rapid heart rate. Take oral mycophenolate mofetil on an empty stomach, at least 1 hour before or 2 hours after a meal. It isnt known how many people may have had unexplained weight loss after using CellCept in clinical studies. (Mycophenolate is the active drug in CellCept). CellCept is typically taken twice daily. Wear protective clothing and hats and stay out of direct sunlight, especially between the hours of 10 am. (Cyclosporine is also an antirejection drug.). If you have neutropenia, your doctor may suggest for you to follow special guidelines, which can help protect you from bacteria and other harmful organisms found in some food and drinks. For this reason, its important to keep taking CellCept and other antirejection drugs for as long as your doctor prescribes them. * The CellCept IV infusion is used for people who arent able to swallow CellCept capsules, tablets, or liquid. Mycophenolate will lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. Below are examples of off-label uses for CellCept. If youre interested in finding an alternative to CellCept, talk with your doctor. hyperglycemia (high blood sugar) high or low blood pressure. Use healthy fats like olive oil, avocado and nut butters to add . The IV infusion should be given within 24 hours of a transplant. The expiration date helps guarantee that the medication is effective during this time. Does CellCept interact with my other drugs? This can make CellCept less effective. No, you shouldnt donate blood while taking CellCept. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Throw away any unused suspension after 60 days. The generic is considered to be as safe and effective as the original drug. A live vaccine contains a weakened form of the virus or bacteria that it helps prevent infection from. * Both drugs are used with other immunosuppressants, such as corticosteroids and cyclosporine. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. However, a universally-accepted definition of what foods should be included was never developed. Source: bing.com. Here are some of the most dangerous food-drug interactions that pharmacists can help prevent: 1. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. CellCept has boxed warnings for pregnancy, serious infections, and cancers. Most people who have had organ transplants take CellCept both right after transplantation and for the long term. Your reason for needing an organ transplant can also affect the amount of alcohol thats safe for you to drink. Below are lists of medications that can interact with CellCept. This is because exposure to the CellCept powder or liquid may cause congenital anomalies (also known as birth defects) or pregnancy loss. All rights reserved. This can raise your risk for side effects from drugs that are cleared through kidney tubules. Talk with your doctor about whether youre up to date on all recommended vaccines before starting CellCept. Its important to note that pregnancy registry data is self-reported, meaning the results are submitted by people taking the drug. For more information, see the CellCept for preventing organ rejection after a transplant section above. Avoid sunlight or tanning beds. However, clinical studies have shown CellCept to be an effective treatment for this condition in adults and in children. You should take CellCept according to your doctors or healthcare professionals instructions. When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. A pregnancy registry helps gather information on how certain drugs can affect pregnancy. Along with its needed effects, a medicine may cause some unwanted effects. CellCept contains the active ingredient mycophenolate mofetil. Depression is a possible side effect of CellCept. Call your doctor right away. Stomach or bowel problems (eg, ulcers, bleeding)Use with caution. Cerner Multum provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. Use sunscreen or sunblock lotions with a sun protection factor (SPF) of at least 30 on a regular basis when you are outdoors. Taking CellCept with certain birth control pills can make these pills less effective. Taking CellCept with cholestyramine (Prevalite) can make CellCept less effective by lowering the amount of CellCept in your body. In some cases, your doctor may lower your CellCept dosage or have you stop treatment with the drug. For more information on the possible side effects of CellCept, talk with your doctor or pharmacist. If you are a woman who can bear children, your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. For more information and to find out if youre eligible for support, call 833-CellCept (833-235-5237) or visit the drug manufacturers website. Ask your doctor if you have any questions. Ask your doctor or pharmacist if you do not understand these instructions. People who Your birth control pills may not work as well while you are using this medicine. . CellCept's mild side effects include: constipation. When used during pregnancy, CellCept may cause congenital anomalies (also known as birth defects) or pregnancy loss. This medicine may inhibit the ability to drive and use machines. This helps ensure you have a consistent amount of the drug in your body. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. (Cancer is a possible serious side effect of CellCept. This medicine may cause serious stomach or bowel problems (eg, ulcers, bleeding). Other symptoms of anemia may include chest pain, shortness of breath, headache, and irregular or fast heart rate. minced chicken or fish in a sauce. omelets or egg scrambles. Weight gain is also a possible symptom of organ rejection. It is used with other medicines (eg, cyclosporine, steroid medicine) to lower the body's natural immunity in patients who receive organ transplants (eg, kidney, heart, or liver). Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. For oral dosage forms (capsules, suspension, or tablets): ChildrenUse and dose must be determined by your doctor. Both CellCept and Myfortic are FDA-approved to help prevent organ rejection after a kidney transplant in adults and in children. In these cases, your doctor may want to change the dose, or other precautions may be necessary. For example, if youve had a liver transplant because of alcohol misuse, your doctor may tell you to stop drinking alcohol entirely. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. This includes prescription or nonprescription (over-the-counter [OTC]) medicines . Organ rejection occurs when the immune system attacks a transplanted organ. Ask your healthcare professional how you should dispose of any medicine you do not use. These may be symptoms of acute inflammatory (swelling) syndrome. This date is typically 1 year from the date they dispensed the medication. ), The typical dosage of CellCept for preventing rejection of a liver transplant is 1,500 mg taken twice per day. The recommended oral dosages in children are as follows: If you miss a dose of CellCept, take your missed dose as soon as you remember. However, you should still check with your doctor or pharmacist before using any of these products while taking CellCept. Dont take an extra dose to make up for your missed dose. Safe preparation and handling of foods is more important than restricting intake of specific food groups, as balanced diet and nutrition is important for coping with chemotherapy and other treatments. They may also recommend a different treatment option for you during pregnancy. You may wonder how CellCept compares with other medications that are prescribed for similar uses. CellCept contains the active drug mycophenolate mofetil. How does blood work, and what problems can occur? Dose is usually not more than 720 mg 2 times a day. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Check with your doctor right away if you have black, tarry stools, constipation, diarrhea, heartburn, indigestion, nausea, stomach pain, cramping, or burning, trouble breathing, or vomiting of blood or material that looks like coffee grounds. Mycophenolate mofetil is sometimes given to pregnant women. Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Its important to note that your childs results may vary from those seen in clinical trials. If you experience weight gain while using CellCept, tell your doctor. It can take up to 12 weeks for CellCept to start working to help prevent organ rejection. Children 5 years of age and older (at least 6 months after the transplant)Dose is based on body surface area (BSA) and must be determined by the doctor. The forms of CellCept that are swallowed are all typically taken twice per day. Examples of birth control pills that contain levonorgestrel include Seasonique and Twirla. Learn more about its effectiveness and. Using alcohol or tobacco with certain medicines may also cause interactions to occur. However, if they become more severe or dont go away, talk with your doctor or pharmacist. For more information on these side effects, see Side effect details below. Because CellCept weakens your immune system, getting a live vaccine while taking CellCept can make the live vaccine less effective. Ask your doctor for any special instructions. This article provides several useful tips on medication disposal. This form of Prograf is also typically taken twice per day. Do not freeze. FDA Warns of Safety Issues With Compounded Forms of Semaglutide, New Study Finds DOs and MDs Provide the Same Level of Care in Older Adults, Cellcept (Mycophenolate Mofetil (Oral/Injection)), Read Cellcept (Mycophenolate Mofetil (Oral/Injection)) Reviews. Call your doctor right away if you have serious side effects. Call your doctor right away. In clinical studies of adults, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo (a treatment with no active drug). Mayo Clinic does not endorse any of the third party products and services advertised. All rights reserved. You must use two forms of birth control together for 1 month before starting this medicine, for the entire time that you are being treated, and for 6 weeks after you receive your last dose of this medicine. A kitchen timer can work, too. It belongs to a group of medications called immunosuppressants. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If your dose is different, do not change it unless your doctor tells you to do so. However, data from pregnancy registries shows that 45% to 49% of people who took CellCept while pregnant had a pregnancy loss in the first 3 months of their pregnancy. If youre taking a form of CellCept thats swallowed, in most cases you should take it on an empty stomach. You may report side effects to FDA at 1-800-FDA-1088. It works by suppressing the immune system, which can make the . For more information, see the Boxed warnings section above.) Having symptoms of organ rejection doesnt necessarily mean that your transplant has failed or that youll need another transplant. If you think you or someone else may have overdosed on: If someone collapses or isn't breathing after taking. *) Talk with your doctor about whether or not your condition is stable enough to take this drug with food. * CellCept and Prograf have boxed warnings for these side effects. Do not use two doses at one time. No, CellCept isnt a chemotherapy drug. Download or order The Leukemia & Lymphoma Societys free fact sheet. In clinical studies of people using CellCept with other immunosuppressant drugs: The percentage of people who may have developed cancer while taking other treatments in these studies isnt known. They can tell you about other medications that may work well for you. Its approved for use in adults and children ages 3 months and older. Colchicine works by decreasing swelling and lessening the build up of uric acid crystals that cause pain in the affected joint (s).This medication is also used to prevent attacks of pain in the . The capsule forms of both drugs are typically taken twice per day. Mild side effects of CellCept can include:*. COMMON BRAND NAME (S): CellCept * The IV infusion is used for people who arent able to swallow CellCept capsules, tablets, or liquid. To learn about the cost of CellCept infusion, talk with your doctor. (For more information on the drugs side effects, see CellCept side effects above.). These lists dont include all possible side effects that may occur with each drug. It is very important that your doctor check your progress at regular visits. You must not donate blood or sperm while using this medicine, and for at least 6 weeks (for blood) or 90 days (for sperm) after your last dose. If you miss a dose of this medicine, take it as soon as possible. The amount of medicine that you take depends on the strength of the medicine. CellCept and Prograf are prescribed for similar uses. Whilst you're taking mycophenolate, tell your doctor, rheumatology nurse or pharmacist straight away if you start experiencing any new symptoms or anything that concerns you. Get Pain Relief With the Most Common Arthritis Medications. This happens because the immune system doesnt recognize the new organ as part of your body. Both drugs belong to a group of medications called immunosuppressants (drugs that weaken your immune system). They can discuss with you the risks and benefits of continuing your CellCept treatment. This means taking your dose either 1 hour before eating or 2 hours after eating. It also helps keep the drug from harming the environment. If you arent having any symptoms of organ rejection, you may not notice CellCept working in your body. Examples of antacids that contain magnesium hydroxide or aluminum hydroxide include: To lower the risk of this interaction, its recommended that you take antacids at least 2 hours after your dose of CellCept. Storage requirements for CellCept vary with each formulation: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Note: The IV infusion is used for people who cannot swallow CellCept capsules, tablets, or liquid. CellCept is an antirejection drug that works by preventing immune cells from multiplying. a stomach ulcer or problems with digestion, diabetes; hepatitis B or C or other viral infection (may become active or get worse while you are using mycophenolate mofetil); phenylketonuria, or PKU. This can make CellCept less effective. For more information about using CellCept to treat scleroderma, talk with your doctor. If you're on the medication, how do you take them? You also shouldnt donate semen while taking this drug. For information on how the drug performed in clinical studies, see CellCepts prescribing information. Cellcept Descriptions Mycophenolate belongs to a group of medicines known as immunosuppressive agents. However, chemotherapy drugs cant tell the difference between healthy cells and cancer cells. UseCellcept (Mycophenolate Mofetil (Oral/Injection))exactly as directed on the label, or as prescribed by your doctor. Your doctor will determine the best dosage to fit your needs. Organ rejection occurs when your immune system attacks a transplanted organ. All rights reserved. Thoroughly cook eggs (no runny yolks) and avoid foods containing raw eggs such as raw cookie dough or homemade mayonnaise. CellCept works by preventing immune cells from multiplying. If you have questions about using CellCept with antacids, talk with your doctor. J Exp Clin Cancer Res. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. (For more information, see the Taking CellCept with food section below.). https://www.mayoclinic.org/drugs-supplements/mycophenolate-mofetil-oral-route/precautions/drg-20073191, Advertising and sponsorship opportunities, Bacillus of Calmette and Guerin Vaccine, Live, Bone marrow problems (eg, neutropenia) or. If you need financial support to pay for CellCept, or if you need help understanding your insurance coverage, help is available. Both drugs were given with corticosteroids and cyclosporine (Neoral). Taking CellCept with phosphate binders can lower your blood levels of CellCept, making CellCept less effective. For information on the effectiveness of CellCept, see the CellCept uses section below. Is the ketogenic diet right for autoimmune conditions? However, swelling in the ankles, feet, or legs can occur with this drug. However, if you do have any of these symptoms, tell your doctor right away so they can treat your condition. If you had astem cell transplant, your diet may be stricter than that of a patient who hadchemotherapyorradiation therapyand no transplant. Find out how it works, what can go wrong, and how to. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. This medicine may cause reactivation of hepatitis B or C infection. Greasy foods: like pizza, cheeseburgers, and donuts. This is a very rare condition where the body no longer makes red blood cells and the patient has severe anemia. CellCept and Prograf are both brand-name drugs. If you have unused medication that has gone past the expiration date, talk with your pharmacist about whether you might still be able to use it. brown rice. What is this medication? If you stop taking CellCept suddenly, you may have a serious side effect called organ rejection. If you can, avoid people with infections. You should take it for as long as your doctor decides its safe and effective for you. Possibly. (For more information, see the CellCept side effects section above.). Mycophenolate mofetil is also used with other medicines to prevent organ transplant rejection. Tell them about all prescription, over-the-counter, and other drugs you take. This works in cancer treatment because cancer cells grow more quickly than normal healthy cells. treatment to maintain immunosuppression for lung transplant ; prevent kidney transplant rejection ; liver transplant rejection prevention Ask your doctor or pharmacist if you have any questions about this. This may occur if you develop an infection or have an existing infection that worsens. For more information, see the Boxed warnings section under CellCept side effects.. Ask your doctor if you have any questions. To learn about other mild side effects, talk with your doctor or pharmacist, or view CellCepts Medication Guide. Highly trained oncology social workersand nurses. For oral dosage forms (delayed-release tablets): Adults720 milligrams (mg) 2 times a day. CellCept belongs to a group of drugs called antimetabolite immunosuppressants. However, it can also happen several years after the transplant. These drugs make your body less likely to reject a transplanted organ. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Weight gain wasnt a side effect reported in clinical studies of CellCept. Investigating the power of music for dementia. This happens because the immune system doesnt recognize the new organ as part of your body. The insurance company will review the prior authorization request and decide if the drug will be covered. Sevelamer (Renvela, Renagel) is an example of a phosphate binder. Although not all of these side effects may occur, if they do occur they may need medical attention. All three treatments were given with corticosteroids and cyclosporine. Cook meat until it's well-done. This lowers your immune systems ability to attack the newly transplanted organ. In clinical studies, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo (a treatment with no active drug) in adults whod had a heart transplant. Kidney disease, severeUse with caution. These infections may lead to serious outcomes, including the need to be hospitalized, and even death. CellCept has been found effective for preventing organ rejection after a heart, kidney, or liver transplant in adults and children ages 3 months and older in combination with other immunosuppressants. This helps make sure you dont transfer the powder or liquid to a surface that might be touched by someone whos pregnant. The risk of pregnancy loss is highest during the first 3 months of pregnancy. If you take too much CELLCEPT,call your doctor or the poison control center right away. Check with your doctor right away if you have a fever and sore throat, pale skin, unusual bleeding or bruising, or unusual tiredness or weakness. Do not freeze the medication. Appropriate studies have not been performed on the relationship of age to the effects of mycophenolate capsules, suspension, or tabletsin children receiving heart or liver transplants. These lists contain up to 10 of the most common mild side effects that can occur with each drug, or with both CellCept and Prograf (when taken individually). To learn more, call 800-617-8191, visit the registry website, or talk with your doctor. It isnt known how many people who used a placebo may have had depression. You should avoid eating at least 1 hour before and 2 hours after taking CellCept. If you are able to get pregnant, you must use specific forms of birth control to prevent pregnancy while using mycophenolate mofetil, and for at least 6 weeks after your last dose. If you would like to notify the FDA about a side effect youve had with CellCept, you can do so through MedWatch. How long a medication remains good can depend on many factors, including how and where you store the medication. For more information about taking CellCept during pregnancy, see the CellCept and pregnancy section above. Congenital anomalies that were reported include facial abnormalities such as cleft lip and palate, and heart defects. You must remain under the care of a doctor while you are using mycophenolate mofetil. They can discuss ways to lower your risk. The injectable formulation is also contraindicated in people who have an allergy to Polysorbate 80 (TWEEN). Avoid unpasteurized beverages, such as fruit juice, milk and raw milk yogurt. (Phosphate is a chemical that naturally occurs in the body.). Prograf contains the active ingredient tacrolimus. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Taking CellCept with drugs that are cleared from the body in this way can increase the levels of these drugs in your body. CellCept is a type ofimmunosuppressant drug (also known as an antirejection drug). If you are also using antacids that contain aluminum or magnesium (eg, Maalox or Mylanta), do not use them at the same time as mycophenolate. Pregnancy tests should be repeated and discussed with your doctor routinely during follow-up visits. Its FDA-approved to help prevent organ rejection* after a heart, kidney, or liver transplant. Lesch-Nyhan syndrome (rare genetic disease)Should not be used in patients with these conditions. Also wear clothing that covers your skin, such as a hat and a long-sleeved shirt. This can lead to side effects from the chemotherapy drug. Tell your doctor about any weight loss that you experience while using CellCept. Information for this minor interaction is available on the professional version. To learn about using Prograf in children, talk with your childs doctor. Also, right after your healthcare professional has used a syringe, needle, or autoinjector, theyll dispose of it in an FDA-approved sharps disposal container. Yes, CellCept may be used off-label to treat lupus. Its time to maximum concentration, maximum concentration, and total exposure are variable with dosing, transplant types, renal function, and kidney function. The following information is provided for clinicians and other healthcare professionals. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Avoid soft mold-ripened and blue-veined cheeses such as Brie, Camembert, Roquefort, Stilton, Gorgonzola and Bleu or other soft, unpasteurized cheeses. There are 7 disease interactions with tacrolimus which include: diabetes mellitus hepatic dysfunction infections QT interval prolongation renal dysfunction hyperkalemia hypertension Report options Use anti-bacterial soap and warm water, scrubbing your hands for 20 seconds. To learn more, see the CellCept use with other drugs section. They may want to monitor you more closely to make sure the medication is working for you. Myfortic contains the active ingredient mycophenolic acid. If youre receiving the CellCept IV infusion, the dose is given by your doctor over a period of about 2 hours, twice per day. This medicine may increase your risk of developing rare and serious virus infections, including shingles, herpes, cytomegalovirus (CMV) infection, polyomavirus associated nephropathy (PVAN), BK virus-associated nephropathy (BKVAN), or SARS-CoV-2 (COVID-19) infection. Serious inflammatory response, which can develop weeks to months after starting treatment or after a dosage increase. Tell your doctor right away if you have any signs of depression while using CellCept. Should a spill occur, wipe it up using paper towels wetted with water to remove the powder or liquid. CellCept is approved to help prevent organ rejection in children ages 3 months and older after a heart, kidney, or liver transplant, in combination with other immunosuppressants. Everyday Health is among the federally registered trademarks of Everyday Health, Inc. and may not be used by third parties without explicit permission. Do not receive a "live" vaccine while using mycophenolate mofetil. There is 1 alcohol/food/lifestyle interaction with mycophenolate mofetil. There arent any known interactions between CellCept and alcohol. Highly clinically significant. You should have one pregnancy test right before starting CellCept and another one 8 to 10 days later. Sexually active men and their partners should use effective contraception during treatment and for at least 90 days after the last dose. The actual price youll pay for any of these drugs depends on the form you use, your treatment plan, your insurance plan, your location, and if applicable, the pharmacy you use. These lists dont include all possible side effects that may occur with each drug. Its prescribed to adults and children ages 3 months and older. For this reason, your doctor will likely need to prescribe other antibiotics to treat your infection. It helps decrease pain, tenderness,. These symptoms may start gradually and get worse quickly. Avoid sunlamps and tanning beds. (Skin spots may be discolored, scaly, or crusty.). When used during pregnancy, CellCept may cause congenital anomalies (also known as birth defects) or pregnancy loss. As a way of protecting your body, your immune system will try to get rid of it. Sodium (salt) increases water retention associated with unsightly cellulite, while potassium has the opposite effect. Use only the dosing syringe provided with this medicine. Possible symptoms of infection include: In clinical studies of adults, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo. Your doctor may want to monitor your treatment with CellCept more closely. Researchers are also looking into other uses. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. A generic drug is an exact copy of the active drug in a brand-name medication. Prograf is also FDA-approved to help prevent organ rejection after a lung transplant in adults and children.. Using this medicine may increase your risk of getting skin cancer or cancer of the lymph system (lymphoma). The results showed that: It isnt known how many people may have had a rash after using a placebo or after using CellCept for other types of transplants. In clinical studies of adults, CellCept was compared with azathioprine and a placebo (a treatment with no active drug). 2014 Mar 5;33:24. In clinical studies of adults, CellCept was compared with azathioprine (Azasan, Imuran). Capsules should be stored at room temperature. Measure the oral liquid medicine with the oral dispenser. In a clinical study of children ages 3 months and older, CellCept was given with corticosteroids and cyclosporine. This is because drinking alcohol can lead to health problems that cause extra strain on your transplanted organ, such as hypertension (high blood pressure). Mycophenolate can cause a number of side effects, including: feeling sick. Specifically, CellCept is a type of immunosuppressant called an antirejection drug. After 12 months of treatment: These results were similar to the results observed in adults using CellCept for kidney transplants. Tax Identification Number: 13-5644916, Long-Term and Late Effects For Cancer Survivors, Diet Guidelines For Immunosuppressed Patients, Employment Rights of Cancer Survivors and Caregivers. Call your doctor for medical advice about side effects. Male patients with female partners should use an effective form of birth control during treatment and for at least 90 days after the last dose. Mycophenolate may cause pure red cell aplasia (PRCA). Using more than the recommended dosage of CellCept can lead to serious side effects. You and your doctor should report your pregnancy to the Mycophenolate Pregnancy Registry either: by phone at 1-800-617-8191 or Your doctor can determine if youre taking a birth control pill that contains levonorgestrel. This medicine comes with patient instructions about the most effective non-hormonal forms of birth control to use. However, this drug hasnt been studied in breastfeeding people. The following lists contain some of the key side effects that may occur while taking CellCept. Keep prepared snacks or small meals on hand and visible. Both types of infusions are given by your doctor. Specifically, CellCept and Prograf are a type of immunosuppressant called antirejection drugs. * Organ rejection occurs when the immune system attacks a transplanted organ. Minor multivitamins with minerals mycophenolate mofetil Minor Drug Interaction Information for this minor interaction is available on the professional version. Do not double doses. 1996-2023 Everyday Health, Inc., a Ziff Davis company. CellCept is also available as tablets and as a liquid that you swallow. Swallow the capsule or tablet whole and do not crush, chew, break, or open it. Ask your doctor about using an additional barrier form of birth control (condom, diaphragm, cervical cap, or contraceptive sponge) to prevent pregnancy. a rare inherited enzyme deficiency such as Lesch-Nyhan syndrome or Kelley-Seegmiller syndrome. Specifically, CellCept and Myfortic are a type of immunosuppressant called antirejection drugs. (Scleroderma is a condition that affects the bodys skin and tissues.) I find it interesting when people take Cellcept (who aren't transplant patients trying to avoid organ rejection) for longer than the 18-24 months that are stated as usage limits. Phenylketonuria (PKU)The oral suspension contains aspartame (phenylalanine), which can make this condition worse. No, CellCept tablets or capsules cant be crushed, split, or chewed. diarrhea. Kelley-Seegmiller syndrome (rare genetic disease) or. CellCept has a boxed warning for the risk of congenital anomalies and pregnancy loss. To learn about the cost of the CellCept infusion and Prograf granules, talk with your doctor or pharmacist. These lists contain up to 10 of the most common mild side effects that can occur with each drug, or with both CellCept and Myfortic (when taken individually). Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. However, unexplained weight loss can also be a sign of cancer. This means taking your dose either 1 hour before eating or 2 hours after eating. Prograf injection should be discontinued as soon as you are able to take the oral form of Prograf. Each infusion is given by your doctor over a period of about 2 hours. Here, learn about the components of blood and how it supports human, The immune system defends the body from invaders such as viruses, bacteria, and foreign bodies. You dont have to avoid eating any specific type of food during your CellCept treatment. Even while taking CellCept or other antirejection drugs, youll likely have at least one episode of organ rejection after a transplant. Serious side effects from CellCept can occur. The BK virus may affect how your kidneys work and cause a transplanted kidney to fail. Talk to your doctor if you have concerns about this risk. stomach pain, nausea, vomiting, diarrhea, constipation, swelling in your ankles or feet, rash, pain anywhere in your body; headache, dizziness, tremors, fever, sore throat, cold symptoms, or other signs of infections; or. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. In a review of studies, the neutropenic diet was never proven to decrease exposure to bacteria in foods. In this article, we will explore some of the foods to avoid while taking Cellcept, as well as the reasons behind these recommendations. It isnt known if CellCept can pass into breast milk. Calcium-Rich Foods + Antibiotics Dairy products such as milk, yogurt, and cheese can interfere with certain medications, including antibiotics such as tetracycline, doxycycline, and ciprofloxacin. You should understand how the drug affects you before driving. The LLS mission: Cure leukemia, lymphoma, Hodgkin's disease and myeloma, and improve the quality of life of patients and their families. Basic Guidelines to Follow Avoid raw or rare meat and fish and uncooked or undercooked eggs. In some cases, the brand-name drug and the generic version may come in different forms and strengths. Minor multivitamins with minerals mycophenolate mofetil Minor Drug Interaction Information for this minor interaction is available on the professional version. And generics tend to cost less than brand-name drugs. High-fat dairy products: like ice cream, cream, butter, and some cheeses. In this situation, your doctor may give you the CellCept infusion for up to 14 days. This drug comes with several precautions. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. If youre concerned about getting a serious infection while using CellCept, talk with your doctor. Both drugs were given with corticosteroids and cyclosporine (Neoral, Sandimmune). There is 1 alcohol/food/lifestyle interaction with CellCept (mycophenolate mofetil). fever of 100.5 degrees F or higher, swollen glands, painful mouth sores, cold or flu symptoms, headache, ear pain, loss of smell or taste, stomach pain, vomiting, diarrhea, weight loss; weakness on one side of your body, loss of muscle control, confusion, thinking problems, loss of interest in things that normally interest you; pain around the transplanted kidney, pain or burning when you urinate, dark urine, jaundice (yellowing of the skin or eyes); tingly or painful blistering rash on one side of your body, swelling, warmth, redness, or oozing around a skin wound; or. MYCOPHENOLATE MOFETIL (mye koe FEN oh late MOE fe til) is used to decrease the immune system's response to a transplanted organ. My doctor specified that I have to take the pills without food, but after researching the pill I found that a lot of people eat food with the pill to settle their stomach. CellCept contains the active ingredient mycophenolate mofetil. A generic drug is an exact copy of the active drug in a brand-name medication. Many of these side effects may go away within a few days or a couple of weeks. It just didn't work for me to take it on an empty stomach, and my Dr okay'd me taking it with food -- AND it put me into "remission". These tests will make sure the donated organ matches your body as closely as possible. Here we look at how CellCept and Myfortic are alike and different. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving mycophenolate. High-Fat Foods. Data sources include IBM Watson Micromedex (updated 14 May 2023), Cerner Multum (updated 28 May 2023), ASHP (updated 10 Apr 2023) and others. Tell your doctor if you have any kind of infection before you start using this medicine. This means taking your dose either 1 hour before eating or 2 hours after eating. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of mycophenolate in the elderly. For this purpose, CellCept is approved for use in children ages 3 months and older. Your doctor may prescribe a different treatment for your condition. * Sex and gender exist on spectrums. As with all medications, the cost of CellCept can vary. Off-label use is when a drug thats FDA-approved to treat one condition is used to treat a different condition. They can give you tips on how to deal with any side effects that may be bothersome. There are 6 disease interactions with CellCept (mycophenolate mofetil) which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. A single copy of these materials may be reprinted for noncommercial personal use only. If you experience a rash while using CellCept, talk with your doctor. Sugary foods and drinks. These side effects may go away during treatment as your body adjusts to the medicine. MNT is the registered trade mark of Healthline Media. These include: Note: For more information about the potential negative effects of CellCept, see the CellCept side effects section above. Use of the term male in this article refers to sex assigned at birth. CellCept Interactions Alcohol/Food Print Save CellCept and Alcohol/Food Interactions There is 1 alcohol/food/lifestyle interaction with CellCept (mycophenolate mofetil). And if you have these side effects, it may help to avoid certain foods. Nuvoli B, Santoro R, Catalani S, et al. Mycophenolate can temporarily lower the number of white blood cells in your blood, which increases the chance of getting an infection. Call your doctor right away if you have: Also call your doctor at once if you have: This is not a complete list of side effects and others may occur. CellCept is available as a generic drug called mycophenolate mofetil. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. CellCept Interactions Print Save CellCept Interactions There are 308 drugs known to interact with CellCept (mycophenolate mofetil), along with 6 disease interactions, and 1 alcohol/food interaction. If youre taking CellCept or Myfortic tablets, or other forms of CellCept that are swallowed, in most cases you should take them on an empty stomach. However, safety and efficacy have not been established in children younger than 5 years of age. stop taking CellCept. CellCept is available as a generic drug called mycophenolate mofetil. Controlling high blood. you are allergic to any other medicines, foods, dyes or preservatives. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. However, Ofev commonly causes digestive side effects such as diarrhea, nausea, and vomiting. In this instance, the CellCept infusion can be administered for up to 14 days. See the CellCept and pregnancy section below to learn about the risks of taking this drug during pregnancy. You should not use this medicine if you are allergic to mycophenolate mofetil, mycophenolic acid, or polysorbate 80. Glipizide is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. (Having a stable transplant means you arent experiencing any symptoms of organ rejection. Refrigerate pate, cold hot dog or deli meat (including dry-cured salami and deli prepared salads containing these items), eggs or seafood. Its available in the following forms and strengths: The first oral dose of CellCept should be given as soon as possible after a kidney, heart, or liver transplant. In clinical studies: In these studies, it isnt known how many people may have died from a serious infection while using other treatments. CellCept has boxed warnings for these side effects. Do not take other medicines unless they have been discussed with your doctor. The most common symptom of anemia is fatigue. Here we look at how these drugs are alike and different. They also included problems with the esophagus, kidneys, nervous system, and abnormalities of the arms and legs. Heres some detail on certain side effects this drug may or may not cause. This card may help lower the cost of the drug for you. Mycophenolate mofetil can make birth control pills less effective. * Organ rejection occurs when the immune system attacks a transplanted organ. They make your body less likely to reject a transplanted organ. The dose is 400 mg per square meter [m(2)] 2 times a day. To help prevent organ rejection, dont stop taking CellCept without first discussing the risks with your doctor. Do not use more CellCept than your doctor recommends. It can be prescribed after a heart, kidney, or liver transplant with other immunosuppressant drugs. Generics tend to cost less than brand-name drugs. Its also available as an intravenous (IV) infusion* (an injection into a vein over a period of time) thats given by your doctor. Examples of immunosuppressants used with CellCept include corticosteroids and cyclosporine (Neoral, Sandimmune). * Some may be a better fit for you than others. Your healthcare team may refer to these guidelines as a neutropenic diet or you may have encountered the term on your own. Generic Name: apixaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat () or after hip/, part of the Uses Warnings: Do not stop taking apixaban unless. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. Maintain good hygiene People who are on immunosuppressant medications should make sure to wash their hands thoroughly and often. The results showed that: The percentage of adults who had anemia after taking these drugs varied depending on the condition being treated. CellCept is FDA-approved to help prevent organ rejection in children ages 3 months and older. Note: Some of the drugs listed here are used off-label to treat these specific conditions. stomach pains. However, as soon as youre able to swallow CellCept capsules, tablets, or liquid, your doctor will likely stop giving you the infusion form. If you have questions, talk with your doctor about the best times to use your medicines. A generic drug is an exact copy of the active drug in a brand-name medication. Other interactions can increase side effects or make them more severe. . The liquid medicine may also be stored in the refrigerator. Prograf is also available in granules that are mixed with water to form a liquid that you swallow. The following information includes only the average doses of this medicine. (Cyclosporine is another antirejection drug.). Infection (eg, bacteria, fungus, or virus), activeMay decrease your body's ability to fight an infection. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It is indicated for use in adults and children ages 3 months and older. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. The vaccine may not work as well and may not fully protect you from disease. The use of CellCept and Myfortic in preventing organ rejection after kidney transplant has been directly compared in a clinical study. For more information, see Boxed warnings under Side effect details below. Rejection is when the body's immune system perceives the new organ as a "foreign" threat and attacks it. Chemotherapy drugs work by destroying all cells that are growing quickly. Youll likely take CellCept twice per day. Enter your information to receive occasional news and important updates! As with most drugs, some people can have an allergic reaction after taking CellCept. Cellcept belongs to a group of drugs called immunosuppressive agents. CellCept is an immunosuppressant (a drug that weakens your immune system). When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Mycophenolate mofetil drug interactions There are 308 drug interactions with mycophenolate mofetil. Check with your doctor right away if you have vision changes, loss of coordination, clumsiness, memory loss, difficulty speaking or understanding what others say, and weakness in the legs. 2. Follow your doctor's orders or the directions on the label. 2011 Sep;49(9):2292-8. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Side effects that were more common in children include: For more information on these side effects, see the Mild side effects and Serious side effects sections above. Cook meat until it's well-done. Your doctor will do blood tests to make sure that mycophenolate is working properly and to check for unwanted effects. Usually avoid combinations; use it only under special circumstances.
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